Numbing Creams Can Make Piercings Pain-Free—We Love These 8 (2025)

TL;DR

The best numbing cream is the Zensa Numbing Cream. It works quickly, keeps you pain-free for hours, and won’t irritate sensitive or broken skin. We also love the more affordable CVS Health Maximum Strength Lidocaine Pain Relief Cream, which provides effective pain relief for only $11.

Beauty is pain, right? Whether it’s piercings, microneedling, laser hair removal, or injectables, the majority of beauty procedures can be an unpleasant and uncomfortable experience. That’s why we’re so grateful to numbing creams, which can be a lifesaver for those with low pain tolerance. “Numbing creams work by temporarily blocking nerve signals in the skin, making the area less sensitive to pain during aesthetic procedures,” says NYC-based plastic surgeon Dr. Robert Schwarcz. “They make treatments more comfortable and help to reduce visible downtime.”

To determine which numbing creams are best, we conducted hours of research and spoke with an aesthetician and plastic surgeon on what makes an effective formula. After considering multiple options, we landed on these top picks.

What We Like

  • Powerful and long-lasting

  • Approved by estheticians

  • Doesn’t cause irritation

What to Consider

  • Small amount for the price

Key Ingredients: Lidocaine 5%, vitamin E | Type: Cream | Size: 1 oz | Cruelty-Free: Yes

If you’re looking for an all-around excellent numbing cream that can be used for all cosmetic services (including laser hair removal), we recommend this pick from Zensa. It comes recommended by aestheticians and piercers, who love its long-lasting, effective formula that doesn’t irritate. It can also be used on broken skin, so it’s safe to reapply post-piercing without damaging it. Aside from the active ingredient lidocaine, it has vitamin E in the formula to promote healing and limit inflammation. While it’s somewhat pricey for a small amount of product, the potent formula that can be used for various treatments makes it worth it.

What We Like

  • Maximum strength, fast-acting formula

  • Shopper favorite

  • Safe for sensitive skin

What to Consider

  • Wears off quickly

Key Ingredients: Lidocaine 5% | Type: Cream | Size: 1 oz | Cruelty-Free: Yes

With over 3,000 five-star ratings on Amazon, the Dr. Numb cream comes highly recommended by shoppers for its powerful and versatile formula. Containing 5% lidocaine alongside lecithin and vitamin E, it protects from pain while soothing the skin. Reviewers love how quickly it works and how well it can totally numb the skin in instances of extreme pain, and many noted that it’s especially effective for needles—making it a great choice for piercings or microneedling. It can wear off after a few hours, so we wouldn't recommend it for large tattoos or other procedures that can take multiple hours.

What We Like

  • Under $15 and accessible

  • Nongreasy and nonirritating

  • No strong smell

What to Consider

  • Not as long-lasting

Key Ingredients: Lidocaine HCI 4% | Type: Cream | Size: 2.7 oz | Cruelty-Free: Yes

Numbing creams can cost you a pretty penny, so we love this one from CVS for an affordable and accessible option. For only $11, you’ll get an effective lidocaine cream that efficiently reduces pain as well as pricier picks. Reviewers love that it’s easy to apply and doesn’t feel greasy on the skin, and it doesn’t have a strong odor like many numbing creams can. While it needs to be reapplied after a few hours for more relief, we think it’s a great, budget-friendly choice for mild pain.

What We Like

  • Made with soothing ingredients

  • Works quickly

  • Effective on intense pain

What to Consider

  • Can leave a film on the skin

Key Ingredients: Lidocaine | Type: Cream | Size: 2 oz | Cruelty-Free: Yes

Beauty procedures can often cause inflammation and irritation, which can be made worse if you already have sensitive skin. This cream from Uber Numb blocks pain and soothes the skin with allantoin and vitamin E—two ingredients great for anti-inflammation and calming. It works quickly—in about 20 minutes—to numb the skin, and it keeps the affected area pain-free for hours. It can leave the skin feeling a little sticky initially, but it absorbs after a minute.

What We Like

  • Promotes healing and soothes irritation

  • Nourishing formula

  • Made with naturally-derived ingredients

What to Consider

  • Thick, slightly hard to spread

Key Ingredients: Shea butter, coconut oil, green tea extract | Type: Cream | Size: 5 oz | Cruelty-Free: Yes

Pain often lingers well after your piercing appointment, and this aftercare balm from Hustle Butter can help. Formulated with coconut oil, shea butter, aloe, and other plant-derived ingredients, it soothes and nourishes the skin—accelerating the healing process. It has a thick formula, making it a little difficult to apply, but the consistency feels comforting on the skin and leaves it soothed for hours. The lovely mango scent is just another plus.

What We Like

  • Works quickly to numb intense pain

  • Vegan formula

  • Soothes and reduces swelling

What to Consider

  • Jar can be hard to open

Key Ingredients: Lidocaine 5% | Type: Cream | Size: 5.5 oz | Cruelty-Free: Yes

If you’re preparing for extreme pain and need something that works quickly and effectively, this Welmate cream is your best bet. Multiple online reviewers named it their go-to, saying it works just as well, or even better, as prescription pain creams. The vegan formula also contains vitamin E and lecithin to relieve irritation and swelling. It works almost instantly to stop pain in its tracks and can be applied up to six times a day. We wish the container were a little easier to open, but it’s still a great product nonetheless.

What We Like

  • Numbs the skin quickly

  • Affordable

  • Hydrating

What to Consider

  • Doesn’t last that long

Key Ingredients: Lidocaine 5% | Type: Cream | Size: 1 oz | Cruelty-Free: Yes

In a pinch? Reach for this numbing cream. It kicks in as little as five minutes, and reaches its full power in about 20 minutes—much faster than other options on the market. The cream itself is water-based, so it feels lightweight on the skin and doesn’t leave a sticky residue behind. It also keeps the skin hydrated with aloe, allantoin, and propylene glycol. Since it doesn’t keep pain at bay for that long, we recommend it for quick procedures—like lobe piercings.

What We Like

  • Numbs pain for hours

  • Comes with a lot of product

  • No smell

What to Consider

  • Difficult to get the cap off

Key Ingredients: Lidocaine 5% | Type: Cream | Size: 6 oz | Cruelty-Free: Yes

This long-lasting pick can numb the area for up to four hours, so you don’t have to worry about reapplying once your appointment is over. At 6 ounces, it has double the product of the majority of other options while still being affordable. Online reviewers also love that it doesn’t leave a greasy feel on the skin, and it even works to reduce itchiness. The childproof cap can be difficult to lift at first, but we think the squeeze bottle makes for an easy application without causing a mess.

What to Look For in a Numbing Cream for Piercings

  • Ingredients: The main ingredient in over-the-counter creams is usually lidocaine—a local anesthetic that can be applied topically. You may also find ingredients such as benzocaine, prilocaine, or tetracaine. “These ingredients are known best for temporarily dulling sensation on the surface of the skin,” says licensed aesthetician Shantani Smith-Pannell. Most options have a 4-5% concentration, but you can find ones by prescription that are higher—which should only be used under the guidance of a healthcare professional, according to Dr. Schwarcz. You’ll also commonly find ingredients that soothe inflammation or irritation in the ingredient list, such as vitamin E, allantoin, and aloe vera. To further avoid irritation, Smith-Pannell says to steer clear of formulas with harsh additives or artificial fragrance.
  • Formula: While creams are a popular format for numbing agents, some brands also offer numbing sprays. Sprays are great for hard-to-reach spots and easy reapplication, but we recommend creams for more precise application and larger areas.

FAQ

  • What’s the best way to apply a numbing cream?

    “Always start with clean, dry skin,” says Smith-Pannell. “Apply a thick, even layer of the numbing cream over the area you’re targeting and cover it with plastic wrap to help it absorb and activate.” The plastic wrap can trap in heat to speed up the numbing process, so make sure not to miss that step, she notes. Follow the label instructions to see how long you should leave it on, and make sure to wipe off completely before your procedure.

  • Is numbing cream for immediate pain or recovery pain?

    “Numbing cream is intended for immediate pain prevention, meaning it's used before a procedure to reduce discomfort during the actual treatment,” says Smith-Pannell. If you’re dealing with pain post procedure, she says you can use a cold compress over your numbing cream of choice to treat any sensitivity.

  • How long does a numbing cream take to work?

    Smith-Pannell says this varies between each product and brand, but on average, they take about 20-30 minutes to kick in for full effect. She recommends following the listed time directions without cutting it short if you want it to work at its full power. Doing so could lead to discomfort for whatever you’re getting done.

Meet Our Experts

We spoke with the following expert to determine what makes a great numbing cream:

  • Dr. Robert Schwarcz, M.D., is a New York-based plastic surgeon.
  • Shantani Smith-Pannell is a licensed aesthetician at Rochelle Aesthetics. She’s based in Atlanta.

Why Trust Byrdie

Shannon Stubbs is a writer at Byrdie, where she covers beauty and more. To write this article, she conducted research and reached out to experts to learn more about numbing creams. She’s been on staff since 2022.

Numbing Creams Can Make Piercings Pain-Free—We Love These 8 (2025)

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